The Robins are 17/10 to take all three points from the Proact Stadium, with the draw 12/5.
Chesterfield, without a win in their last four league outings, have lost three of those games by one goal and Swindon are 7/2 to edge the spoils by a single goal.
Spireites striker Eoin Doyle leads the goalscoring charts in the division with 14 to his name already and is 4/1 to net first and even-money any time on Tuesday.
Swindon’s Michael Smith isn’t too far behind having notched eight thus far and he’s 9/2 to break the deadlock.
Top Tip: Both teams to score at 8/13