Last season, the Town drew the home game but were beaten in the away game which enabled the Grecians to finish as runners-up, one point ahead of third-placed Town. To date, Exeter have won two and lost two and are in sixth spot.
Manager Steve Robertson said: "This is a game where we probably won’t start as favourites. We only took one point off them last year so I think that we will need to up our game to get anything from the fixture. We have several players missing but I am sure that those coming in will take their chance to secure a permanent place in the team."
The Town will be without Meg Vella, Sam Quinn, Michelle Rich and the injured Laura Morgan.
SQUAD: Robyn Levett, Alice Smith, Alex Hurst, Natasha Perry, Serena Smith, Ellie Maynard, Sarah Uzzell, Chyna Collings, Beth Westlake, Abby Picton, Chenise Austin, Sally Butterfield and Meg Attenborough.